The Spanish Flu strain of the H1N1 infected humans during the period of 1916-1918 and killed 50 million people before a vaccine was found. An adapted version of the virus called HPAI A(H5N1) is one of the highly virulent types and is the causative agent of Bird flu. It had a mortality rate of about 50% as compared to the H1N1 strain which has a mortality rate of 5%.3
Perhaps the most striking resemblance is that the last 3 codes of the virus have revealed similarities to the current H5N1 strain also known as Bird Flu. Recent changes in the genome of the H5N1 virus have sparked fears that co-infection with H1N1 may cause a pandemic among populations.1
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