For the purposes of this study the objective was quantify the benefits and harms of adding clopidogrel to standard long term aspirin therapy for preventing cardiovascular events in people at high risk cardiovascular diseases and those with established cardiovascular diseases.
Randomized control trials to compare long-term use of aspirin plus clopidogrel with aspirin plus placebo for the patients described above were included with a follow up of up to 30days. The study involved aspirin plus clopidogrel versus aspirin plus placebo or aspirin alone. No other platelet aggregation inhibitors as co-intervention were accepted.
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