An error of metabolism which occurs as a result of phenylalanine is called Phenylketonuria (PKU). In this disorder the enzyme phenylalanine hyroxylase iud deficient in the body. This enzyme converts phenylalanine into tyrosine. As a result of this deficiency, the metabolites build up in the blood and body tissues. The brain is the most affected tissue.

The symptoms for this usually include seizures, inability to talk/walk and mental retardation. A restricted diet is essential to reduce the symptoms from being so severe.

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